The storage and handling conditions printed on the vial or carton labels may differ from those in approved WHO product information. In these circumstances, the conditions in the product information should be followed

WHO Product Information for Dilute to use, 12 years and older, Purple Cap and Package, Multi-dose vial

The shelf life for COMIRNATY is 24 months when stored at -90 °C to -60 °C. In order to determine appropriate expiry date, please first check the date printed on vials and cartons.

If the date printed on the vials and cartons reflects the date of manufacture (MFG)
In this case vaccine vials should not be used after 24 months from the date of manufacture (MFG) printed on the vials and cartons. Please refer to the table below to determine the appropriate expiry date based on the printed date of manufacture (MFG):  

^a - Expiry date update combining 9, 12- and 15-,18-months and 24 months shelf-life extension.
^b - Due to implementation of the change in shelf-life from 6 to 9 months in October 2021, three different printed expiry dates could be extended to September 2023.
c - Applicable to batch with printed expiry date May 2022 corresponding to 9-months shelf-life; two different printed expiry dates could be extended to August 2023.

If you observe a vial and carton label that says expiry date (EXP) on it, the guidance above does NOT apply. Please review the guidance regarding EXP dates below.

If the date printed on the vials and cartons reflects the date of expiry (EXP) and if that date is February 2022 or earlier
In this case the expiry date is in the past and before WHO's authorisation of 18- to 24-month extension, therefore the vials should not be used. Please note that per standard regulatory principles, WHO does not recommend use of vaccines beyond their labelled expiry date.

If the date printed on the vials and cartons reflects the date of expiry (EXP) and if that date is March 2022 or later
In this case please refer to your local regulatory authority to determine whether your local regulatory authority has allowed the acceptance of vaccine batches impacted by retroactive shelf-life extension from 18 months to 24 months. Please note that per standard regulatory principles, WHO does not recommend use of vaccines beyond their labelled expiry date. If there is express permission of the local regulatory authority, please refer to the table below to determine the appropriate expiry date based on the printed date of expiry (EXP): 

^a - Expiry date update combining 9, 12- and 15-,18-months and 24 months shelf-life extension.
^b - Due to implementation of the change in shelf-life from 6 to 9 months in October 2021, three different printed expiry dates could be extended to September 2023.
c - Applicable to batch with printed expiry date May 2022 corresponding to 9-months shelf-life; two different printed expiry dates could be extended to August 2023.
 

The storage and handling conditions printed on the vial or carton labels may differ from those in approved WHO product information. In these circumstances, the conditions in the product information should be followed

WHO Product Information for 12 years and older, Ready to use Grey Cap and Package
WHO Product Information for 12 years and older, Ready to use Grey Cap and Package, Original/Omicron BA.1
WHO Product Information for 12 years and older, Ready to use Grey Cap and Package, Original/Omicron BA.4-5
WHO Product Information for 5 to 11 years of age, Dilute to use, Orange Cap and Package, Multi-dose vial
WHO Product Information for 5 to 11 years of age, Dilute to use, Orange Cap and Package, Multi-dose vial, Original/Omicron BA.4-5

The shelf life for COMIRNATY is 24 months when stored at -90 °C to -60 °C. In order to determine appropriate expiry date, please first check the date printed on vials and cartons.

If the date printed on the vials and cartons reflects the date of manufacture (MFG)
In this case vaccine vials should not be used after 24 months from the date of manufacture (MFG) printed on the vials and cartons. Please refer to the table below to determine the appropriate expiry date based on the printed date of manufacture (MFG):  

^a – Expiry date update combining 9,12- and 18-and 24-months shelf-life extension
b - Expiry date update combining 12- and 18- and 24-months shelf-life extension

If you observe a vial and carton label that says expiry date (EXP) on it, the guidance above does NOT apply. Please review the guidance regarding EXP dates below.

If the date printed on the vials and cartons reflects the date of expiry (EXP) and if that date is February 2022 or earlier
In this case the expiry date is in the past and the vials should not be used. Please note that per standard regulatory principles, WHO does not recommend use of vaccines beyond their labelled expiry date.

If the date printed on the vials and cartons reflects the date of expiry (EXP) and if that date is March 2022 or later
In this case please refer to your local regulatory authority to determine whether your local regulatory authority has allowed the acceptance of vaccine batches impacted by retroactive shelf-life extension from 18 months to 24 months. Please note that per standard regulatory principles, WHO does not recommend use of vaccines beyond their labelled expiry date. If there is express permission of the local regulatory authority, please refer to the table below to determine the appropriate expiry date based on the printed date of expiry (EXP): 

^a - Expiry date update combining 9, 12- and 18- and 24-months shelf-life extension
^b - Due to implementation of the change in shelf-life from 6 to 9 months in December 2021, three different printed expiry dates could be extended to November 2023.
^c - Expiry date update combining 12- and 18- and 24-months shelf-life extension
^e - Printed expiry date assigned automatically by SAP system based on system calculation algorithm

All vials with an expiry date of March 2025 and beyond will already reflect the 24 months shelflife.